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Product Description

Similac Pro-Total Comfort* is our most gentle formula with 2’-FL human milk oligosaccharide (2’-FL HMO), an immune-nourishing prebiotic like that found in breast milk that supports baby’s developing immune system. It’s an easy-to-digest formula for delicate tummies and a good choice for babies who have difficulty tolerating other milk-based formulas.

* Not for infants or children with galactosemia.

  • LESS FUSSINESS & CRYING: Parents reported§ a significant reduction in fussiness, gas, and crying after just 1 day of feeding
  • GENTLE FORMULA + IMMUNE SUPPORT: Similac Pro-Total Comfort is our most gentle formula with 2’-FL HMO, a prebiotic that helps strengthen your baby’s immune system
  • SUPPORTS BRAIN & EYE DEVELOPMENT: Features our exclusive blend of DHA, lutein, and vitamin E, ingredients found in breast milk that are important for helping to support baby’s brain and eye development
  • PROMOTES STRONG BONES: Has no palm olein oil to promote excellent calcium absorption for strong bones
  • TRUSTED BRAND: Similac is the #1 infant formula brand chosen by parentsǁ
  • NO ARTIFICIAL GROWTH HORMONES & NON-GMO#: Similac is the first leading infant formula brand with no artificial growth hormones. Similac Pro-Total Comfort contains ingredients that are not genetically engineered

* Not for infants or children with galactosemia.
Not from human milk.
At significant levels.
§ After switching to Similac Pro-Total Comfort.
Total US infant formula, all outlets as of 6/2020, Nielsen data.
No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.
# Ingredients not genetically engineered.

Ingredients & Nutrition

Allergen Statement

Contains milk ingredients.

Ingredients

Corn Maltodextrin, Whey Protein Hydrolysate, High Oleic Safflower Oil, Sugar, Soy Oil, Coconut Oil. Less than 2% of: C. Cohnii Oil, M. Alpina Oil, 2'-Fucosyllactose, Short-chain Fructooligosaccharides, Beta-Carotene, Lutein, Calcium Citrate, Potassium Phosphate, Calcium Phosphate, Salt, Magnesium Chloride, Ascorbic Acid, Choline Chloride, m-Inositol, Potassium Chloride, Sodium Citrate, Calcium Hydroxide, Potassium Citrate, Choline Bitartrate, Ferrous Sulfate, Taurine, Zinc Sulfate, Ascorbyl Palmitate, L-Carnitine, Niacinamide, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Copper Sulfate, Vitamin A Palmitate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Potassium Iodide, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Potassium Hydroxide, and Nucleotides (Adenosine 5’-Monophosphate, Cytidine 5’-Monophosphate, Disodium Guanosine 5’-Monophosphate, Disodium Uridine 5’-Monophosphate).

Serving Size: 100 Cal (5 fl oz, prepared as directed)

Nutrient Data

Nutrient Data

Amount per serving
% Daily Value*
Calories
100
 
Volume, mL
148
 
Protein, g
2.32
 
Fat, g
5.4
 
Carbohydrate, g
10.7
 
Water, g
133
 
Linoleic Acid, mg
1000
 

Vitamins

Amount per serving
% Daily Value*
Vitamin E, IU
1.5
 
Vitamin K, mcg
8
 
Thiamin (Vitamin B1), mcg
100
 
Riboflavin (Vitamin B2), mcg
150
 
Vitamin B6, mcg
60
 
Vitamin B12, mcg
0.25
 
Niacin, mcg
1050
 
Folic Acid (Folacin), mcg
15
 
Pantothenic Acid, mcg
450
 
Biotin, mcg
4.4
 
Vitamin C (Ascorbic Acid), mg
9
 
Choline, mg
24
 
Inositol, mg
24
 
Vitamin A, IU
300
 
Vitamin D, IU
60
 

Minerals

Amount per serving
% Daily Value*
Calcium, mg
105
 
Calcium, mEq
5.3
 
Phosphorus, mg
75
 
Magnesium, mg
6
 
Iron, mg
1.8
 
Zinc, mg
0.75
 
Manganese, mcg
5
 
Copper, mcg
90
 
Iodine, mcg
15
 
Selenium, mcg
2
 
Sodium, mg
44
 
Sodium, mEq
1.9
 
Potassium, mg
118
 
Potassium, mEq
3
 
Chloride, mg
65
 
Chloride, mEq
1.8
 

Serving Size: 1000 mL (1.1 QT, prepared as directed)

Nutrient Data

Nutrient Data

Amount per serving
% Daily Value*
Calories
676
 
Volume, mL
1000
 
Protein, g
15.68
 
Fat, g
36.49
 
Carbohydrate, g
72.3
 
Water, g
899
 
Linoleic Acid, mg
6757
 

Vitamins

Amount per serving
% Daily Value*
Vitamin E, IU
10.1
 
Vitamin K, mcg
54.1
 
Thiamin (Vitamin B1), mcg
676
 
Riboflavin (Vitamin B2), mcg
1014
 
Vitamin B6, mcg
405
 
Vitamin B12, mcg
1.69
 
Niacin, mcg
7095
 
Folic Acid (Folacin), mcg
101.4
 
Pantothenic Acid, mcg
3041
 
Biotin, mcg
29.7
 
Vitamin C (Ascorbic Acid), mg
60.8
 
Choline, mg
162.2
 
Inositol, mg
162.2
 
Vitamin A, IU
2027
 
Vitamin D, IU
405
 

Minerals

Amount per serving
% Daily Value*
Calcium, mg
709
 
Calcium, mEq
35.8
 
Phosphorus, mg
507
 
Magnesium, mg
40.5
 
Iron, mg
12.16
 
Zinc, mg
5.07
 
Manganese, mcg
33.8
 
Copper, mcg
608
 
Iodine, mcg
101
 
Selenium, mcg
14
 
Sodium, mg
297
 
Sodium, mEq
12.8
 
Potassium, mg
797
 
Potassium, mEq
20.3
 
Chloride, mg
439
 
Chloride, mEq
12.2
 
Reviews

Similac Pro-Total Comfort Infant Formula Powder

Product Comparison

What is the difference between Similac Pro-Total Comfort vs other formula types?

Similac Pro-Total Comfort™* Infant Formula, with 2’-FL HMO for Immune Support, Easy-to-Digest, Non-GMO, Baby Formula, Powder, 20.1 oz

Similac Pro-Total Comfort™* Infant Formula, with 2’-FL HMO for Immune Support, Easy-to-Digest, Non-GMO, Baby Formula, Powder, 20.1 oz

Similac Pro-Sensitive®* Infant Formula, with 2’-FL HMO for Immune Support, Non-GMO, Baby Formula, Powder, 1.41 lb

Similac Pro-Sensitive®* Infant Formula, with 2’-FL HMO for Immune Support, Non-GMO, Baby Formula, Powder, 1.41 lb

Similac® Alimentum® Hypoallergenic Infant Formula, for Food Allergies and Colic, Baby Formula Powder, 19.8-oz Can (Case of 4)

Similac® Alimentum® Hypoallergenic Infant Formula, for Food Allergies and Colic, Baby Formula Powder, 19.8-oz Can (Case of 4)

Description
A gentle formula with 2’-FL HMO, an immune-nourishing prebiotic
First formula with 2’-FL HMO for sensitive tummies
For babies with food allergies and colic symptoms due to protein sensitivity
Complete Nutrition for Infants
Selected
Selected
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Suitable for Lactose Sensitivity
Selected
Selected
Selected
Eases Fussiness & Gas Due to Lactose Sensitivity
Selected
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Partially Hydrolyzed Whey Protein for Easy Digestion
Selected
Has 2’-FL HMO for Immune Support
Selected
Selected
Hypoallergenic for Cow’s Milk Allergy
Selected

* Not for infants or children with galactosemia.

FAQs

What is the difference between Similac Pro-Total Comfort* and Similac Pro-Sensitive*?

Similac Pro-Sensitive* has intact milk protein, while Similac Pro-Total Comfort* has 100% whey protein that is partially hydrolyzed as an alternative to standard intact-protein, milk-based formulas. 

What’s the difference between Similac Pro-Advance*, Similac Pro-Sensitive*, Similac Pro-Total Comfort*, and other Similac baby formulas?

Similac Pro‐Advance* is our closest formula to breast milk. Similac Pro‐Advance*, Similac Pro‐Sensitive*, and Similac Pro-Total Comfort* have 2’-FL HMO (human milk oligosaccharide), a unique immune-nourishing prebiotic. Other Similac baby formulas also provide complete nutrition for babies, but it’s up to parents, along with their doctor, to choose which formula to feed their baby.  Learn more 

What does Similac Pro-Total Comfort* help with?

Similac Pro-Total Comfort* with 2’-FL HMO is an easy-to-digest, gentle baby formula. It’s designed for babies who have difficulty tolerating other milk-based formulas and mild tolerance symptoms, such as fussiness and gas due to lactose sensitivity.

* Not for infants or children with galactosemia.
Not from human milk.

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