Similac® Formulas with 2’-FL HMO Are Inspired by Breast Milk

Similac Pro-Advance®, Similac Pro-Sensitive®, and Similac Pro-Total Comfort™ are the first Similac formulas with 2’-FL HMO,* a prebiotic like that found in most breast milk. 2’-FL HMO supports a baby’s immune system to be more like that of a breastfed infant.

Because you promise to give your baby a strong start—we make formulas that help you keep that promise.

Discover the Similac difference in Similac Pro-Advance, Similac Pro-Sensitive, and Similac Pro-Total Comfort.

  • 2’-FL HMO* for immune support

          A prebiotic that helps strengthen your baby’s immune system to be more like a breastfed infant than ever before1-3 

  • DHA, lutein, and vitamin E

         Also found in breast milk, these nutrients help support your baby’s brain & eye development

  • No Palm Olein Oil

        Similac has no palm olein oil to support excellent calcium absorption and stronger bones

  • No Artificial Growth Hormones

        Similac formulas have no artificial growth hormones

  • Non-GMO

         Our products contain ingredients that are not genetically engineered

Have more questions about 2'-FL HMO?*

Learn more about the benefits of 2’-FL HMO in our FAQs.

See FAQs

* Not from human milk.
No significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows.
Ingredients not genetically engineered.
References: 1. Goehring KC, et al. J Nutr. 2016;146(12):2559-2566. 2. Schaller JP, et al. Pediatr Res. 2004;56(6):883-890. 3. Buck RH, et al. Pediatr Res. 2004;56(6):891-900.

Find the Perfect Formula

Our products are made with your baby’s unique needs in mind. Choose from hypoallergenic, soy, and organic formulas, as well as other specialized nutrition options.

Join Similac®  StrongMoms® Rewards

Get up to $400* in savings, nutrition guidance, ongoing tips and education, plus a FREE Shutterfly photo book!


Offers may vary.
Submit registration to read details.

The Promise of Similac

We promise to help keep your baby fed, happy, and healthy.

Join Similac® StrongMoms® Rewards. It’s fast and FREE!

Postnatal Popup
  • Formula Samples
  • Information about your baby’s milestones
  • Free Shutterfly® photo book
  • Exclusive savings on Schedule & Save purchases

Submit registration to read details.

Join Similac® StrongMoms® Rewards. It’s fast and FREE!

Prenatal Popup
  • Free Shutterfly® photo book
  • Nutrition guidance for your pregnancy
  • Information about your baby’s milestones

Submit registration to read details.

Instead of paper coupons, receive Similac® digital offers

Digital Offers Popup

Now you can switch to digital savings by phone on your favorite formulas—here’s how:

  1. Choose a preferred retailer, like Amazon or Target
  2. Get notified about offers via email